All entries for Monday 16 October 2023
October 16, 2023
New Preprint! BeAST and Yeast!
Excited to share this new preprint!
Bioelectrical antimicrobial susceptibility testing (BeAST) with the budding yeast S. cerevisiae
Congratulations to Tailise and the team! This was a great collaboration with Tasic lab @Unicamp, Brazil (more collaboration to be followed, hopefully!)
In this work, we investigated how membrane potential of yeast changes after stimulated with an externally applied electric field. We found that non-inhibited cells show a hyperpolarisation upon electric stimulation. Interestingly, the magnitude of hyperpolarisation correlates with the level of growth inhibition. Thus, we propose this could be used as a Bio-electrical AST.