BeAST – Bio–electrical Antimicrobial Susceptibility Testing

New paper is out!

Membrane potential dynamics unveil the promise of bioelectrical antimicrobial susceptibility Testing (BeAST) for anti-fungal screening

https://journals.asm.org/doi/10.1128/mbio.01302-24

Munehiro Asally : 23 Jul 2024 15:22 |  Comments (0) |  Close comments |  Report a problem

New preprint – Fungi oscillation

Emergence of synchronised growth oscillations in filamentous fungi

https://doi.org/10.1101/2023.12.22.573137

Munehiro Asally : 09 Jan 2024 13:07 |  Comments (0) |  Close comments |  Report a problem

COVER! ThT and mitochondrial membrane potential

Emily's paper is now published in Biophysical Reports and feature on the front cover!!

https://doi.org/10.1016/j.bpr.2023.100134

Munehiro Asally : 13 Nov 2023 17:28 |  Comments (0) |  Close comments |  Report a problem

Talent wanted!

Looking for aspiring students to join the lab to work on excitng PhD projects!

Please get in touch with Munehiro if you have any queries.

Molecular mechanism of bacterial electrical signalling

Bringing light to bacterial electrophysiology – bacterial optogenetics

Electrogenetics – engineering living electronic transducer protein

Munehiro Asally : 31 Oct 2023 16:28 |  Comments (0) |  Close comments |  Report a problem

New Preprint! BeAST and Yeast!

Excited to share this new preprint!

Bioelectrical antimicrobial susceptibility testing (BeAST) with the budding yeast S. cerevisiae

Congratulations to Tailise and the team! This was a great collaboration with Tasic lab @Unicamp, Brazil (more collaboration to be followed, hopefully!)

In this work, we investigated how membrane potential of yeast changes after stimulated with an externally applied electric field. We found that non-inhibited cells show a hyperpolarisation upon electric stimulation. Interestingly, the magnitude of hyperpolarisation correlates with the level of growth inhibition. Thus, we propose this could be used as a Bio-electrical AST.

https://doi.org/10.1101/2023.10.05.561038

Munehiro Asally : 16 Oct 2023 16:56 |  Comments (0) |  Close comments |  Report a problem

Phase separated nuclear bodies

A collobration paper with Oka-san has been published in Cell Reports.

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure

https://www.sciencedirect.com/science/article/pii/S2211124723008951

Munehiro Asally : 04 Aug 2023 18:56 |  Comments (0) |  Close comments |  Report a problem

Great news! Study featured by Biomedical Picture of the Day (BPoD) and New Scientist!

Tailise's Ziapin2 movie has been choosen as "Biomedical Picture of the Day" on 2023/3/13.

Thanks for selecting our movie and congratulations Tailise and the team!

https://bpod.mrc.ac.uk/archive/2023/3/13

The study has also been featured by New Scientist!

https://www.instagram.com/reel/CourMR9tkp3/

https://twitter.com/newscientist/status/1626613914870898693

Munehiro Asally : 16 Mar 2023 12:08 |  Comments (0) |  Close comments |  Report a problem