April 22, 2021

Jan – Apr 2021 (Part 2)

Plans for the rest of the year:

As I write this, I am in the middle of my final exam season of my undergraduate degree!

(Although it’s technically the Easter holidays at the moment, some rescheduling had to be done by the Department in order to give us time to complete our dissertations before the end of the year.)

As almost all my exams are essay based, it’s also been a great way for me to consolidate all the learning I’ve done this year in some very interesting modules, ranging from Biological Clocks to System Dynamics.

After exams, I will undertake my dissertation in “Deep-Learning Microscopy Data Analysis” and then embark on a very interesting Summer research project!

As the wet-lab research component of my internship last year was sadly cancelled, I was set on seeking a lab-based internship for this Summer in order to gain further hands-on experience for my intended career in research. Thankfully, I was able to find a Professor at Life Sciences willing to supervise my application for a £1000 research grant from the University, which I am glad to announce was successful!

As such, later this year I will be exploring whether human mutations of Connexin32 (a protein that forms plasma membrane channels between cells) affect its sensitivity to CO2. This in the context of understanding the biological cause of Charcot-Marie-Tooth disease, a hereditable motor-sensory neurological disorder that progressively reduces quality of life, with symptoms such as numbness of limbs and muscle weakness. Although this disease is not directly life-threatening, it can severely reduce mobility and independence of patients and does not yet have a cure. A major challenge in the development of therapies/cures for this disease is that it comes in many different forms, all with different genetic causes. As such, I hope to add to its current genetic understanding with my project, in order to support the approach towards current and future treatment.

Additionally, I am currently mentoring the new Warwick iGEM team and will continue to do so over the Summer, until the Competition near the end of this year. As my cohort was the first batch having to work through COVID, I would like to help them make a smoother transition to virtual teamworking and biological research!

Volunteering:

Due to schools in the UK being closed for lockdown, we were unfortunately unable to do as much volunteering in BioSoc as originally planned. Societies were made to cancel all in-person activites, and it would have been unsafe for us to travel into schools or carry out hands-on experiments during this time. Doing virtual volunteering was also a difficult task to coordinate as our teacher liaisons reported difficulties finishing the assigned teaching syllabi, let alone putting aside time for us to teach external material to students.

However, in February I was contacted by a member of staff asking for help with the then-upcoming Women in Science Day programme at Warwick as another team of volunteers had pulled out of the project at late notice. As such, we had less than a week’s time to come up with a topic and teaching resources for Year 11 students to explore biology at home.

After deciding to take on the challenge, I recruited a friend on the BioSoc exec to brainstorm and churn out the material over the weekend. We decided to base the activity off fermentation, as we wanted to engage the students through something we all do (eat food) as well as only require materials that are easily found in the home. I created an instruction and tracking sheet teaching students how to make their own sourdough bread starter, which only requires water, flour and time to make. In case they had a teacher running through the programme with them, I also created a short slideshow presentation explaining the science behind fermentation and the creation of sourdough bread.

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Afterwards, we were left scratching our heads trying to figure out how to keep a group of 14/15 year olds interested in our activity through online learning. My friend Jerry came up with the amazing idea to create an Among Us-themed quiz, as Among Us was a incredibly popular game at the time. I once again fell back on my Visual Arts training to design and draw Among Us characters with different foods, much like how the characters have customisable hats in the actual game.

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Jerry the editing whiz did some video-making magic, creating an interactive “choose your adventure” style set of videos for the students to click through. Clicking on the wrong answers would bring them to the game’s end screen, while successful completion of the short quiz would show the game’s Victory screen. After recording further videos explaining how to use the resource pack, we sent it off to the University, hopefully for the young students to enjoy.

Staying at Home:

The heavy snow back in January gave us a welcome excuse to have some fun outside, as my housemates and I spent hours in the garden building my first ever snowman!

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For Christmas and Chinese New Year, we also had cozy celebration dinners in our shared kitchen.

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Overall, despite it being an incredibly busy time, I’ve greatly enjoyed my last year at Warwick so far and will be reluctant to officially leave when graduation comes! Thanks to all the fulfilling endeavours I've been able to carry out this year, I’ve had a good time in the past two terms despite the limitations of lockdown 😁


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