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February 09, 2007

Worcester Sauce (tangy) Twiglets

Follow-up to Marmite from Planned Random Action

After an unusually high number of responses to my marmite thread talking about worcester sauce (tangy) twiglets I’ve decided to try and follow up what has happened to them.

For anyone that doesn’t know, Jacob’s Twiglets are baked wheat snack flavoured with yeast extract (marmite). A few years ago (possibly anywhere up to 10 years) Jacob’s released 2 new flavours of twiglets: Worcester Sauce (which later became Tangy Worcester Sauce) and one that I seem to remember being more garlic and herb flavoured. The latter flavour seemed to disappear fairly quickly as it was probably the case that nobody liked them.

The Worcester Sauce Twiglets were generally well accepted by people and stayed around for a bit longer.

Unfortunately these have also disappeared from shop shelves. Searching the internet has also yielded very few references about them (strangely this blog generally coming out top on google searches).

The only clue to their continued existance is from a tin of Twiglets from Christmas 2006. On the side there is a small panel listing some other products. Included is the Tangy Worcester Sauce Twiglets.

Do you know what happened to Worcester Sauce Twiglets? Have you found any for sale? Can we bring them back?

Regards
Me


January 22, 2007

Anti–ageing cream…

I heard a funny story yesterday…ok, well i found it so…. So an elderly lady made the profound statement that she’s applied anti-wrinkle cream with the same hand for 40 years, and yet when comparing her hands, they’re both as damn wrinkly as each other!!!!.... :-)


December 11, 2006

To highlight

I’d just like to draw attention to my dear friend Vib’s latest entry with which I agree entirely and which I hope many people will read…

(unfortunately I seem to be unable to track back to the entry – Blogs doesn’t like me)

:-(


December 05, 2006

Fraud in the scientific world?

In response to Trev’s heartfelt pleadings and the fact that I haven’t blogged for a VERY long time…

An article decribing some of the comments of Warwick sociology professor Steve Fuller was printed on the front page of the Boar on 7th November (a long time ago, I know). In it, Fuller is said to advocate the use of fraudulent data in scientific research in order to tweak results and make conclusions more convincing. He has even defended the actions of South Korean professor Woo Suk Hwang, who pretended that he had managed to clone a human embryo. He decribes the approach he suggests as ‘idealising’ results rather than ‘fraud’.

The article also details a survey take by Nature in the US which suggests that a third of postgraduate researchers did not follow ethical guidelines in their research. Currently, when articles come to publication, the journal editors have to essentially take them on face value. Fuller argues that we shouldn’t put so much trust in our scientists.

Should we take the scientists’ word for it? Should there be some kind of vetting system aiming to identify fraudulent research? Would measures of this kind ‘slow the pace of science down prohibitively’, as Fuller puts it? How easy would it be possible to maintain some kind of uniform standard in this vetting system? Does the fact that some kind of scientific fraud takes place already, and that eradicating it would be very difficult, justify its existence to the extent that we shouldn’t do anything about it? If you allow some kind of fraud (the ‘tweaking’ of results, for instance) how do you then stop it from going beyond just ‘tweaking’? Can we then trust the scientists to ‘tweak’ their results in the direction of the actual truth (inaccuracies can happen either through intentional bias or just because the data subtly suggests something that on further investigation actually turns out to be fictitious)?


October 20, 2006

Face transplants – an ethical and practical dilemma

The other day I sat down (a relatively rare occurrance at the moment) and watched the Horizon programme about Isabelle Dinoire, the first person to receive a face transplant. Isabelle was mauled by her pet dog, an horrific incident which left her without her lips, part of the flesh on her chin and the bottom half of her nose. Nearly a year ago she underwent the first ever face transplant operation, which was a success.

Whilst Isabelle was, herself, incredibly positive about the operation and its results, a huge amount of contraversy and argument has surrounded the proceedure.

  • Whilst the majority of transplant operations that are currently carried out routinely are life-saving, face transplants are not essential to survival in any way. It the proceedure a luxury that we don’t need?
  • On the other hand, as a result of the way she looked, Isabelle’s life changed dramatically. For example, she had to wear a mask over her face when she went out. Is this deterioration in quality of life enough of a justification?
  • A vastly important consideration in any transplantation proceedure is the risk of rejection. The immune system of the recipient will attack the transplanted tissue unless strong immunosuppressant drugs are taken by the for the rest of their lives. These drugs make the patient more susceptible to infection and increase the risk of cancer. Despite these drugs, there is still a 5% risk of rejection.
  • Along similar lines, a disfigured person (for example a burn victim) will often have large amount of skin and facial tissue left, and may have already undergone many operations to improve their appearance, facial function and comfort. To carry out a face transplant on that patient will mean removing all of their skin and a large amount of the soft tissue order for them to receive the new face. If their immune system then rejects it they would be in a far worse situation than they were before the operation.
  • The other, less tangible, issue is a psychological one. The face is associated far more with identity than any other part of the body. Although the transplanted tissue moulds to the bone structure of the recipient, the face will still be considerably different from their own. Is this too much of a hurdle to jump for some patients? In contrast, some might say that the patient might have already undergone so much adjustment to become accustomed to their disfigured state that making the jump to transplantation is not so great.

August 31, 2006

Obesity and IVF: what do you think?

Writing about web page http://news.bbc.co.uk/1/hi/health/5296200.stm

Yesterday the British Fertlity Society announced recommendations for all seriously obese and underweight women to be refused IVF on the NHS, something that some Primary Care Trusts already practise, in an attempt to homogenise the availability of treatment throughout the country.

Why is it that obese women are being refused IVF? A representative from the BFS has cited a reduced chance of falling pregnant and an increase in complications during the pregnancy itself. Why, then, are women smokers allowed IVF so freely? According to one news report yesterday smokers do have an equal chance of falling pregnant as completely healthy women, but the increased chance of complications is significant. If the mother has a medical condition that causes or at least exacerbates her obesity should she be treated any differently? Should we merely consider the probability of conception or also bear in mind the long-term health of the mother and child?

Or is this starting to infringe on our civil liberties?

The BFS also recommended that single women and same sex couples should be given the same priority as heterosexual couples.

Some PCTs are reported to take into account social factors when deciding if IVF is permitted, including whether either parent has already had children from a previous relationship and whether they have undergone IVF privately before turning to the NHS. Should these factors be taken into account? What if the couple have already had children together and want more?

Should the NHS fund IVF at all? Is having children a right? Is it equal to the right to life-saving treatment of injuries and diseases, bearing in mind that the money for all treatments comes from the same budget, and that the NHS has been beleaguered with many much-publicised financial strains? Or is it a luxury that the parents themselves should fund? Or do you agree with Dr Gillian Lockwood of the BFS ethics committee, that “the fourth richest country on earth should be able to afford effective fertility care for its citizens”.

What do you think?


August 14, 2006

Sperm and responsibility

I'm currently listening to an interesting programme on Radio 4 about the current 'crisis' in sperm donation. Recent law changes have given the children of sperm donors the right to trace their fathers once they reach adulthood. Unsurprisingly, this has significantly decreased the numbers of sperm donors to a critical point.

  • Should a child have the automatic right to find out who their parents are, even in the formerly anonymous and random act of sperm donation?

  • Are the recent changes morally important as they encourage potential donors to really consider the consequences their contribution rather than being principally swayed by the monetary advantages? Is it necessary for a potential donor to consider these issues so seriously?

  • What are the motivating factors for sperm donation and have they now changed?

  • If we accept that the change in the law is morally right how can we overcome the current crisis in sperm availability?

July 31, 2006

A Hum doozy….

OK, so I'm not watching big brother this year, but it's hard not to get sucked into knowing a little bit about it….so basically I was having an interesting conversation with Helen the other day about what will happen after the winner is announced. So, I think I'm right in saying that Pete (the guy with Tourette's) is pretty certain to win. So the question that arose is….will/should he be allowed to give the usual live interviews on day–time tv, like all the other winners in the past?.....the obvious answer is yes of course he should. But what about tv standards – i'm meaning watershed issues. Surely there'll be lots of horrified people complaining about him randomly swearing live on daytime tv. But then, surely u can't discriminate due to illness. An interesting one, and one that tv standards agencies surely can't win, no matter which way they decide…. thoughts?

July 28, 2006

Intriguing, and slightly worrying…

Writing about web page http://www.newscientist.com/channel/being-human/mg19125591.800.html

In a recent New Scientist article about the practicalities of polygamy as a lifestyle choice, a psychology professor said:

Infidelity in monogamous relationships is estimated at 60 to 70 per cent, so it seems that attraction to more than one person is normal.

I found that statistic quite surprising, if not slightly scary… is it really true???

On a different, but not unrelated, point… is the divorce rate going up because more relationships are actually failing? Or is it just because relationships that would previously have been maintained due to the stigma attached to divorce, but that had really failed, are being actively severed? How can we tell?


July 07, 2006

I am a stupid fool…

Hello people… I've had a few blue after Mat's viva party, so I probably shouldn't really say this kinda thing, but I am so so so so so so so annoyed and angry with myself… grrrrrrrrr… cos I had the perfect opportunity to invite FK on a night out this weekend, and I'm sure he wouldn't have said yes anyway, but I couldn't even bring myself to do it… why why why am I so pathetic and worried all the time??? IT'S NOT FAIR… so now we'll both be sat at home lonely on Saturday night, when we could have been having fun… (well, I'd have been having fun and he'd have been thinking, "oh my god what the hell am I doing here"...)... but no, I couldn't even have the bottle to ask him… hence I am a stupid fool… :–(

Anyway, well done Mat, nice one, only two more years to go for me now I guess… yay!!! Bonza…

Good luck to Italia on Sunday by the way…


June 28, 2006

Security

Writing about web page http://www.newscientist.com/article/mg19025556.200?DCMP=NLC-nletter&nsref=mg19025556.200

Thank you to Duncan for sending me a link to the above article.

The internet is a fantastic tool: I myself would feel significantly at a loss without it. It allows you immediate access to a wealth of information, allows instant communication across the globe and transfer of data and ideas.

The advantages for scientists, for instance, could be huge: they will have unprecedented access to each other's experimental datasets and will be able to perform their own analyses on them. Searching for products such as holidays will become easier as price and availability dates will have smart tags, allowing powerful searches across hundreds of sites.

However, a comment was posted on my recent entry suggesting that certain contributors might want to restrict the things they mentioned in a public forum. Whilst I have no problem with people contrubuting in whatever way they like to my blog, I do worry that sometimes we may reveal too much. Several times I have read surprised entries from students who have discovered that their parents read their blogs.

"I AM continually shocked and appalled at the details people voluntarily post online about themselves." So says Jon Callas, chief security officer at PGP, a Silicon Valley–based maker of encryption software. He is far from alone in noticing that fast–growing social networking websites such as MySpace and Friendster are a snoop's dream … "You should always assume anything you write online is stapled to your resumé. People don't realise you get Googled just to get a job interview these days"
New Scientist has discovered that Pentagon's National Security Agency, which specialises in eavesdropping and code–breaking, is funding research into the mass harvesting of the information that people post about themselves on social networks. And it could harness advances in internet technology – specifically the forthcoming "semantic web" championed by the web standards organisation W3C – to combine data from social networking websites with details such as banking, retail and property records, allowing the NSA to build extensive, all–embracing personal profiles of individuals.

There are examples of people who have been sacked from their jobs for revealing details of excessive drinking and drug–taking, and some who have been barred from religious colleges after revealing their homosexuality.

Why do bloggers so readily reveal such information online? Do we really consider the potential readership? Should we be more worried about the information employers and even governments can gather? Did the people mentioned above deserve their dismissal or should their treatment have been more lenient?


June 26, 2006

The morality surrounding Trident

Writing about web page http://www.bbc.co.uk/religion/programmes/thought/documents/t20060626.shtml

I heard, whilst prising myself from a rather deep sleep this morning, the words of Clifford Longley on Thought For The Day. He emphasised the need for a reasoned dialogue to begin about Trident and general nuclear issues.

Catholic bishops in Scotland have started the ball rolling with an outspoken rejection on moral grounds of the whole theory of nuclear weapons. They are just not compatible with God's commandment Thou shalt not kill, they argued, because possessing them entailed a conditional willingness to use them. That means an intention to kill hundreds of thousands of innocent civilians. It is immoral to sign up to such a policy, say the bishops. But if so, how do we defend ourselves from the ultimate threat, a nuclear 9/11 or 7/7? Isn't that a moral duty too?

How exactly do we follow through this moral argument? Is a nuclear weapon morally wrong because of the intention to kill? If so, what about an armed police officer? Yes, they will presumably use is as a last resort and only ever when provoked, but the possibility of injury or even death is still there. I've read many recent comments applauding the killing of Abu Musab al–Zarqawi, the leader of al–Qaeda in Iraq. Granted, he was a brutal murderer and in the opinion of many got what he deserved, but was his killing morally right?

In the hands of politicians, these decisions are going to be reduced to issues of national pride and/or the cost to the taxpayer, or even personality clashes between ministers. As a nation we have to lift our game. Sometimes politics really is too important to be left to the politicians.

How important is the moral debate when weighed up against the other considerations of cost and practicality?


June 18, 2006

The importance of commemoration

I read a comment in a newspaper recently, I can't remember where, in which the author complained about the commemoration of important tragedies: 9/11, 7/7, the world wars etc. He moaned about constantly being forced to remember depressing events.

Another man, Charles Wolfe, who moved to New York in 1979 and lost his wife Katherine who was working inside Tower One on 11 September, said: "I'm ready for the big ceremonies to stop, it is bringing up grief unnecessarily."

I seem to remember an outcry from some at the incredible extent of the mourning following Princess Diana's death. Speaking seven weeks before the anniverary of her death, the Most Rev David Hope, England's second most senior archbishop, called for people to stop "wallowing" in it.

Are we wallowing in the remembrance of tragedies to a greater extent than we have done before? How important is it for us to continue to celebrate the lives and sacrifices of soldiers, disaster victims etc? Does it also serve as an important reminder for future generations? And is any of our commemoration too over–the–top or even utterly inappropriate?


June 15, 2006

Friendliness to strangers

Last weekend Justin and I went for a stroll down the Grand Union Canal – a very pleasant way to spend an hour or two. Whilst we walked I was struck by something I'd almost forgotten about but that I have been intending to blog for quite a while.

Almost every time we came across someone a generation or more above us we exchanged a 'hello', 'good afternoon' or something similar and we even struck up a short conversation with a couple on a passing canal boat. This was the same when I used to go walking and cycling in the South Downs at home. However, I'd probably think twice about doing the same with someone of my own generation. This to me seems to be a real shame.

Why have we stopped being friendly? Is it because we have become more aware of the potential risks posed by strangers? If so, why should someone of the younger generation necessarily pose less of a risk than an older person? Why are we so friendly when out in the countryside, for example, whereas similar exchanges are not usually seen on the streets of a town? Is it the expression of some feeling of companionliness with someone who obviously enjoys a similar pastime?


June 14, 2006

Threatening patriotism?

I heard a comment last week, I think at the beginning of a TV programme I didn't actually stay up to watch, that someone found the abundant England flags that are so prevalent at the moment to be threatening. This interested me.

As a country I don't think we are particularly patriotic any longer. Indeed, as a contrast, Anna remarked on arrival on the other side of the world that the Brazilians for one are incredibly proud of their country and are not backward in showing it. Why do we not fly the flag to the same extent as we once did? Do we feel that it's politically incorrect in some way (do we not express feelings of pride because we feel they are inappropriate or do we really no longer feel so much pride)? Why does it take the advent of a major sporting tournament for us to become so patriotic?

Why on earth should an English person feel so threatened by a flag representing his own country displayed in his own country? Is it because of the association with the darker and more violent side of football that has gained some England supporters unwelcome notoriety? If so why should all displays of patriotism be associated with this minority?


May 30, 2006

The benefits of not finding what you want…

Writing about web page http://news.bbc.co.uk/1/hi/technology/5018998.stm

I found this article on the BBC News website very interesting, not least because it made me think about my own habits.

The idea put forward is that random exposure to subjects, viewpoints and media that you would not usually search for is important in broadening people's horizons and even in increasing their creativity. But is new technology increasing or decreasing the incidence of serendipity it? And is it really that important?


May 24, 2006

Justifying violent crime?

With the current murmerings about the rights of criminals being overplayed and victims being put at extra risk a story in this morning's Metro seemed particularly apt.

Jonathan Wright was assaulted by Michael Donohoe and hit over the dead with a nail–studded post, leaving him with a three–inch gash over his ear. However, when he applied to the Criminal Injuries Compensation Authority for compensation he was turned down because he swore at his assailant. Quoting from the letter of refusal…

Your conduct, in being verbally abusive towards the assailant, was an important factor in the incident.

May 22, 2006

Relationship standards

I had a rather random conversation today, the upshot of which was the following:

  • Why is it that the idea of a woman in a heterosexual relationship being intimate with another women is often relatively acceptable, if not arousing, to their corresponding partners? Why is the reversal involving the partner with another man generally less acceptable to the woman?

  • Why is it that some men don't regard their girlfriend kissing other women as cheating yet if they kissed another man it would be a serious offence?

  • Do men and women have different attitudes towards cheating and does this result in some hypocrisy in the actions of either?

May 19, 2006

Herceptin, H5N1 and drugs trials

I was attempting to avoid the H5N1 bandwagon but it looks like I failed…

Many have complained recently about the coverage of the bird flu story in the media, saying that it has been sensationalist and potentially panic–inducing. This is clearly a difficult subject because whilst the chances of the virus mutating and becoming a transmissible human virus are relatively low, if this does actually happen the resultant pandemic could be terrifying. It depends on how you classify a potential crisis. The BBC has on its forum, as many have highlighted, a series of alarmist comments from members of the public (as well as, presumably, a swathe of others asking everyone to calm down). The BBC and newspapers have been criticised for their own coverage of the situation.

The opening paragraph from a recent New Scientist article read:

I have nothing against miracles, but whenever there's a big buzz about a new drug, it's a fair bet it'll be down to the usual suspects: vested interests, early research, and uncritical journalists.

I'm sure everyone will be aware of the hype surrounding the release, and subsequent variable availability, of the new breast cancer drug Herceptin. The media pronounced it a 'wonder drug', but how many people know the real truth about its successes? The tests carried out showed that Herceptin benefits only a small number of women – shrinking tumours in only 15% of cases – yet the early reports did not make this clear. The trial was carried out on women who had cancers that had been treated early. Emphasising a figure of a 52% reduction in recurrence in a group who already have a small chance of re–contracting the disease is misleading (even those who have no treatment after surgery have a recurrence maximum of 10% per year, dropping to 3% after 10 years). The test groups were also very small – only in the 10s – so the perceived advantages could have been down to pure chance. Yet this drug was described as a potential ‘cure’ by the 2006 President of the American Society of Clinical Oncology: a man who is also a paid consultant to Genentech, Herceptin’s US distributor.

Another important recent medical story was about the drugs trial that left six men critically ill. Many criticisms were voiced at the time criticising and even blaming the manufacturer of the drug. Yet when a follow–up story came out declaring that the manufacturer had followed all the required protocols and was thus not guilty of any negligence it didn't make the BBC News website front page, nor the Science and Nature front page. In fact, I had to do a search to find it.

Now, I don’t begrudge anyone access to a treatment that may save or help to sustain their lives: far from it. However, bearing in mind the huge variation between the hype and the reality in the case of Herceptin I can’t help but think that the injustice has been blown slightly out of proportion. Again with H5N1, there is a balance to be had between the potential risks. But is it the duty of the media to reflect these issues realistically and in a balanced manner? The newspapers need to sell and the TV companies need to maximise viewer ratings, and sensational stories will help with this. However, whereas newspapers are private companies, the BBC is publicly funded and has a Board of Governors who purport to act as ‘trustees of the public interest’. Is it in the public interest for these stories to be reported in a totally balanced manner or should we be expected to draw our own conclusions based on the true facts? How do you ensure a balanced coverage when many important stories may be reported many times, each time with a potentially different slant? Surely the purpose of a forum is to air the views of the public: should the BBC or any other company censor its fora to prevent potential hysteria or is this unfair?


March 18, 2006

Vacation buses

Hello everyone… just thought I'd have a bit of a rant about how rubbish the bus service to Leamington is durind the university vacations… one per hour is simply not good enough in my opinion… it invariably means that I have nothing better to do than hang around in the computer centre and write in this damn thing (not that I ever write in it, but hey, "what can you do???")... all I wanna do is get back home to my packet of ham and bottle of baileys (shock horror, something different…)

I should really report on whats been happening recently, but to be honest it ain't much… the mighty BWFC continue their march towards the Champions League… DCFC lose and LCFC and NFFC both win – NIGHTMARE SCENARIO… have far too much work to do and really can't be bothered… our housemate has abandoned us (good move!!!) for a beautiful new apartment on Clarendon Avenue (can't blame her really, it is an amazing place)... when's Irish bird gonna be around again I wonder…???... and I must remind myself to watch DH tomorrow…

This is becoming far to random, anyone would think I was just crazy… and now if I'm not quick I'm gonna miss the bus!!!


March 13, 2006

Da Vinci Cod

So Dan Brown is being sued for copying from these two guys who wrote a book ages ago? That right? Now, I'm no lawyer or historian, but surely by suggesting that he stole their idea they are also suggesting that they made it up in the first place?? I haven't read their book, but I presume it tries to persuade that the whole Jesus and Mary Magdalene sex scandal is 'fact'. In which case they can't own the idea can they? Isn't that a bit like a scientist saying, "I did this research but u can't write about it even if u reference me (which Brown does in his book)?".......i'm sure i must have missed the point….

January 17, 2006

Top–hasbeen

Went to top-b last night. Oh dear. It really isn't like the old days is it? I know I'm in fear of becoming a grumpy old man, but I don't care. Club-styleeee music (sorry I'm not up with the terminology like trance and the such like – loser I know – but surely a garage is something for a car and a house is somewhere for people to live?) just isn't top-b. It has a time and a place i agree, but top b is cheese? Yes?!....

Anyway – quote of the night goes to me…." Ah yes…cryfield 3 thats the one with a CH3 sign – a methyl group….".....once again – the word loser springs to mind. Also had a 'hilarious' (one of those you had to be there moments) conversation with my housemate in reference to said quote walking to work this morning….something about water being the most terrible of housemates – such a bipolar personality…. my god….how sad are we?


January 03, 2006

Marmite

  • Love
  • Hate
  • No strong feelings either way

Discuss…

Regards
Me


December 19, 2005

Patez's Christmas do…

Hey hey folks, just wanna say cheers to Paulo, Patez and Quiggles (apparently it's officially got two g's) for the impromptu Christmas party tonight, twas much fun indeed… we've had much interesting conversation including pornographic kangaroos… and I can't believe Quiggles just vetoed the Macarena… how upsetting is that??? I'll have to have my revenge at some point… maybe with "Saturday Night" at the biochemistry reunion in January… ha ha ha!!! And does anyone else think Sharon Osbourne is quite fit???

Anyway, I'm gonna report on my weekends away in London and Sheffield at some point, cheers for havin' me Rohan and Elks, they were both very much fun indeed!!! I hope Sameet's ok Ro?!?!? Right, enough semi-drunken rambling, speak to ya soon everyone…


December 07, 2005

Reality gone mad!

Ok, so we've all watched them, and become embarrasingly addicted to them right? I'm talking about those annoyingly addictive reality tv shows like 'Big Brother' and 'I'm a Celebrity'...Well this year I thought of a clever twist to put the sparkle back into these rather dwindling so-called 'intriguining insights into real-life'.

Here's the deal – Take your 10 randomly selected people from 'all walks of life', tell them they're going to be on tv 24/7 and one of them will be a big star when the come out. Then shove them in a small house with some fake cctv cameras, and leave them. Take one of them out every week and let them in on the prank. Clever? I think we should start a petition and send it to these reality tv companies and see what they say…