July 23, 2024

BeAST – Bio–electrical Antimicrobial Susceptibility Testing

New paper is out!

Membrane potential dynamics unveil the promise of bioelectrical antimicrobial susceptibility Testing (BeAST) for anti-fungal screening

https://journals.asm.org/doi/10.1128/mbio.01302-24


January 09, 2024

Fungi oscillation

Now published in Journal of Royal Society Interface!

https://royalsocietypublishing.org/doi/10.1098/rsif.2024.0574


Emergence of synchronised growth oscillations in filamentous fungi

Praneet Prakash, Xue Jiang, Luke Richards, Zoe Schofield, Patrick Schafer, Marco Polin, Orkun S. Soyer, Munehiro Asally


fungi


November 13, 2023

COVER! ThT and mitochondrial membrane potential

Emily's paper is now published in Biophysical Reports and feature on the front cover!!

biophyReportEmily

https://doi.org/10.1016/j.bpr.2023.100134


October 31, 2023

Talent wanted!

Looking for aspiring students to join the lab to work on excitng PhD projects!

Please get in touch with Munehiro if you have any queries.

Molecular mechanism of bacterial electrical signalling


Bringing light to bacterial electrophysiology – bacterial optogenetics

Electrogenetics – engineering living electronic transducer protein


October 16, 2023

New Preprint! BeAST and Yeast!


Excited to share this new preprint!

Bioelectrical antimicrobial susceptibility testing (BeAST) with the budding yeast S. cerevisiae



Congratulations to Tailise and the team! This was a great collaboration with Tasic lab @Unicamp, Brazil (more collaboration to be followed, hopefully!)

In this work, we investigated how membrane potential of yeast changes after stimulated with an externally applied electric field. We found that non-inhibited cells show a hyperpolarisation upon electric stimulation. Interestingly, the magnitude of hyperpolarisation correlates with the level of growth inhibition. Thus, we propose this could be used as a Bio-electrical AST.


August 04, 2023

Phase separated nuclear bodies

A collobration paper with Oka-san has been published in Cell Reports.


Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure

https://www.sciencedirect.com/science/article/pii/S2211124723008951


March 16, 2023

Great news! Study featured by Biomedical Picture of the Day (BPoD) and New Scientist!

Tailise's Ziapin2 movie has been choosen as "Biomedical Picture of the Day" on 2023/3/13.

Thanks for selecting our movie and congratulations Tailise and the team!

https://bpod.mrc.ac.uk/archive/2023/3/13

BPoD



The study has also been featured by New Scientist!

https://www.instagram.com/reel/CourMR9tkp3/

https://twitter.com/newscientist/status/1626613914870898693


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