POSTDOC AND PHD OPPORTUNITIES!

We are recruiting a postdoc and PhD students to join the lab to work on the biophysics of bacterial electrical signalling!

We are privileged to receive research project funding from the Leverhulme Trust. The project will explore the potential synapse-like electrochemical signalling in bacteria. The Leverhulme Trust generously funds a 3-year postdoc and a 3.5 year PhD studentship.

We are looking for people with background/interests in physics of life, soft and active matter physics, quatitative biology, and electrophysiology. Experience in microbiology is not necessary.

For more information about the postdoc position, visit https://www.jobs.ac.uk/job/DLC690/research-fellow-109982-1224

In addition to this, there are fully funded PhD studentship opportunity at MIBTP -Midland Integrative Bioscience Training Partnership. The application deadline for this excellent program is 16 January 2025. I am proposing three projects:

• Investigating heat-based detection and manipulation of bacterial biofilms
• Molecular dynamics of a bacterial potassium channel YugO
• Structural and cellular characterisation of Bacillus subtilis chloride channels

Munehiro Asally : 16 Dec 2024 16:37 |  Comments (0) |  Close comments |  Report a problem

BeAST – Bio–electrical Antimicrobial Susceptibility Testing

New paper is out!

Membrane potential dynamics unveil the promise of bioelectrical antimicrobial susceptibility Testing (BeAST) for anti-fungal screening

https://journals.asm.org/doi/10.1128/mbio.01302-24

Munehiro Asally : 23 Jul 2024 15:22 |  Comments (0) |  Close comments |  Report a problem

Fungi oscillation

Now published in Journal of Royal Society Interface!

https://royalsocietypublishing.org/doi/10.1098/rsif.2024.0574

Emergence of synchronised growth oscillations in filamentous fungi

https://doi.org/10.1101/2023.12.22.573137

Munehiro Asally : 09 Jan 2024 13:07 |  Comments (0) |  Close comments |  Report a problem

COVER! ThT and mitochondrial membrane potential

Emily's paper is now published in Biophysical Reports and feature on the front cover!!

https://doi.org/10.1016/j.bpr.2023.100134

Munehiro Asally : 13 Nov 2023 17:28 |  Comments (0) |  Close comments |  Report a problem

Talent wanted!

Looking for aspiring students to join the lab to work on excitng PhD projects!

Please get in touch with Munehiro if you have any queries.

Molecular mechanism of bacterial electrical signalling

Bringing light to bacterial electrophysiology – bacterial optogenetics

Electrogenetics – engineering living electronic transducer protein

Munehiro Asally : 31 Oct 2023 16:28 |  Comments (0) |  Close comments |  Report a problem

New Preprint! BeAST and Yeast!

Excited to share this new preprint!

Bioelectrical antimicrobial susceptibility testing (BeAST) with the budding yeast S. cerevisiae

Congratulations to Tailise and the team! This was a great collaboration with Tasic lab @Unicamp, Brazil (more collaboration to be followed, hopefully!)

In this work, we investigated how membrane potential of yeast changes after stimulated with an externally applied electric field. We found that non-inhibited cells show a hyperpolarisation upon electric stimulation. Interestingly, the magnitude of hyperpolarisation correlates with the level of growth inhibition. Thus, we propose this could be used as a Bio-electrical AST.

https://doi.org/10.1101/2023.10.05.561038

Munehiro Asally : 16 Oct 2023 16:56 |  Comments (0) |  Close comments |  Report a problem

Phase separated nuclear bodies

A collobration paper with Oka-san has been published in Cell Reports.

Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure

https://www.sciencedirect.com/science/article/pii/S2211124723008951

Munehiro Asally : 04 Aug 2023 18:56 |  Comments (0) |  Close comments |  Report a problem